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Results for "

B-cell receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (1) Antibody-Drug Conjugates (ADCs) (1) Apoptosis (3) BMX Kinase (1) Btk (8) CD19 (5) CD22 (1) EBI2/GPR183 (1) Endogenous Metabolite (4) HCV (1) IRAK (2) Isotope-Labeled Compounds (1) LAG-3 (1) Liposome (2) MALT1 (1) Phosphatase (1) Toll-like Receptor (TLR) (2)
By Research Areas:	Cancer (18) Infection (1) Inflammation/Immunology (19) Metabolic Disease (1)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: Itk TOPK NAMPT ALCAM/CD166 GDNF Receptor BCL6 Tim3

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-147308

PCLX-001 1 Publications Verification	Others	Cancer
PCLX-001 is an orally acitve, small-molecule, dual N-myristoyltransferase (NMT) inhibitor, with IC₅₀s of 5 nM (NMT1) and 8 nM (NMT2), respectively. PCLX-001 exhibits anti-tumor activity and inhibits early B-cell receptor (BCR) signaling, can be used to B-cell malignancies research .

HY-129390

Orelabrutinib ICP-022	Btk	Cancer
Orelabrutinib (ICP-022) is a potent, orally active, and irreversible Bruton's tyrosine kinase (BTK) inhibitor with potential antineoplastic activity. Orelabrutinib prevents both the activation of the B-cell antigen receptor (BCR) signaling pathway and BTK-mediated activation of downstream survival pathways, inhibiting the growth of malignant B-cells that overexpress BTK .

HY-P99338

Tisagenlecleucel CTL019	CD19	Inflammation/Immunology Cancer
Tisagenlecleucel (CTL019) is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. Tisagenlecleucel targets and eliminates CD19-expressing B cells. Tisagenlecleucel can be used for the research of refractory aggressive diffuse large B-cell lymphoma .

HY-160142

UBX-382	Btk	Cancer
UBX-382 is an orally available proteolysis-targeting chimeras (PROTACs) that target BTK to inactivate B-cell receptor signaling. UBX-382 shows superior degradation activity for wild-type and mutant BTK proteins and shows anti-cancer activity in murine xenograft models of TMD-8 cells .

HY-NP006

Protein A SPA	Endogenous Metabolite	Inflammation/Immunology
Protein A (SPA) is an immunoglobulin (Ig) binding protein that exists on the surface of bacteria and can be freely secreted into the extracellular environment. Protein A blocks opsonization and phagocytosis and induces B-cell death in vitro by binding to the Fc region of antibodies and the Fab region of B-cell receptors. Protein A has the ability to inhibit opsonization and phagocytosis in vitro .

HY-153357

NRX-0492	Btk	Cancer
NRX-0492 is an orally active and potent degrader of BTK. NRX-0492 catalyzes ubiquitylation and proteasomal degradation of BTK with DC₅₀≤0.2 nM and DC₉₀≤0.5 nM, respectively. NRX-0492 inhibits B-cell receptor (BCR)-mediated signaling, transcriptional programs, and chemokine secretion. Moreover, NRX-0492 also links a noncovalent BTK-binding domain to Cereblon. Cereblon is an adaptor protein of the E3 ubiquitin ligase complex .

HY-111101

AZ1495	IRAK	Cancer
AZ1495, a weak base, is a potent orally active interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor. AZ1495 has a favorable physicochemical and kinase selectivity for IRAK4 and IRAK1 with IC₅₀ values of 0.005 μM and 0.023 μM, respectively. AZ1495 has IRAK4 inhibition with a K_d value of 0.0007 μM. AZ1495 can be used for the research of diffuse large B-cell lymphoma (DLBCL) .

HY-136268

AQX-435	Phosphatase Apoptosis	Inflammation/Immunology
AQX-435 is a potent SHIP1 phosphatase activator. AQX-435 reduces PI3K activation downstream of the B-cell receptor (BCR) and induces apoptosis of malignant B cells, and reduces lymphoma growth .

HY-P99255

Moxetumomab pasudotox CAT 8015; HA 22	Antibody-Drug Conjugates (ADCs) CD22	Cancer
Moxetumomab pasudotox (CAT 8015) is anti-CD22 immunotoxin containing an anti-CD22 F_v and Pseudomonas exotoxin. CD22 is a cell surface receptor expressed on a variety of malignant B-cells. Moxetumomab pasudotox can be used in the research of hairy cell leukemia (HCL) .

HY-153084

CD19 CAR mRNA	CD19	Inflammation/Immunology Cancer
CD19 CAR mRNA will express CD19 car protein, and can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction.

HY-153085

CD19 CAR circRNA	CD19	Inflammation/Immunology Cancer
CD19 CAR circRNA will express CD19 car protein, and can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction.

HY-147584

BTK-IN-14	Btk	Inflammation/Immunology Cancer
BTK-IN-14 is a potent inhibitor of BTK. BTK plays an important role in signaling mediated by B cell antigen receptor (BCR) and Fcγreceptor (FcγR) in B cells and myeloid cells, respectively. BTK-IN-14 has the potential for the research of related diseases, especially autoimmune diseases, inflammatory diseases or cancer (extracted from patent WO2022057894A1, compound 1) .

HY-147581

BTK-IN-11	Btk	Inflammation/Immunology Cancer
BTK-IN-11 is a potent inhibitor of BTK. BTK plays an important role in signaling mediated by B cell antigen receptor (BCR) and Fcγreceptor (FcγR) in B cells and myeloid cells, respectively. BTK-IN-11 has the potential for the research of related diseases, especially autoimmune diseases, inflammatory diseases or cancer (extracted from patent WO2022063101A1, compound Z2) .

HY-109010

Poseltinib HM71224; LY3337641	Btk BMX Kinase Toll-like Receptor (TLR)	Metabolic Disease
Poseltinib (HM71224) is an orally active, selective, irreversible small molecule Bruton tyrosine kinase (BTK) inhibitor. With an IC₅₀ of 1.95 nM. Poseltinib effectively inhibits the signaling mediated by B cell receptors (BCR), Fc receptors (FcR), and Toll-like receptors (TLR). Poseltinib has anti-inflammatory activity and can be used in the research of rheumatoid arthritis .

HY-113134

25-Hydroxycholesterol Maximum Cited Publications 15 Publications Verification 25-OHC	Endogenous Metabolite	Inflammation/Immunology
25-Hydroxycholesterol (25-OHC) is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC₅₀≈65 nM) and selective suppressor of IgA production by B cells.

HY-153234

CD19 car circRNA-LNP	CD19 Liposome	Inflammation/Immunology Cancer
CD19 car circRNA-LNP is a lipid nanoparticle (LNP) containing CD19 car circRNA, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. CD19 car circRNA can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction .

HY-153233

CD19 car mRNA-LNP	CD19 Liposome	Inflammation/Immunology Cancer
CD19 car mRNA-LNP is a lipid nanoparticle (LNP) containing CD19 car mRNA, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. CD19 car mRNA can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction .

HY-P990046

Tuparstobart Incagn-02385	LAG-3	Inflammation/Immunology
Tuparstobart (Incagn-02385) is an IgG1κ antibody targeting LAG-3. LAG-3 is an immune checkpoint receptor protein mainly expressed on activated T cells, NK cells, B cells and plasmacytoid dendritic cells .

HY-P99487

Briobacept BR 3FC	ADC Antibody	Inflammation/Immunology
Briobacept (BR 3FC) is a selective human monoclonal antibody targeting to BLyS (BAFF), induces B cells apoptosis. Briobacept is a recombinant glucoprotein, consists of 2 molecules from the BLyS receptor (BR3)and a Fc domain of human IgG1. Briobacept can be used in studies of rheumatoid arthritis (RA) .

HY-15771A

Tirabrutinib hydrochloride 3 Publications Verification ONO-4059 hydrochloride; GS-4059 hydrochloride	Btk Apoptosis	Inflammation/Immunology Cancer
Tirabrutinib (ONO-4059) hydrochloride is an orally active Bruton’s Tyrosine Kinase (BTK) inhibitor (can cross the blood-brain barrier (BBB)), with an IC₅₀ of 6.8 nM. Tirabrutinib hydrochloride irreversibly and covalently binds to BTK and inhibits aberrant B cell receptor signaling. Tirabrutinib hydrochloride can be used in studies of autoimmune diseases and hematological malignancies .

HY-15771

Tirabrutinib 3 Publications Verification ONO-4059; GS-4059	Btk Apoptosis	Inflammation/Immunology Cancer
Tirabrutinib (ONO-4059) is an orally active Bruton’s Tyrosine Kinase (BTK) inhibitor (can cross the blood-brain barrier (BBB)), with an IC₅₀ of 6.8 nM. Tirabrutinib irreversibly and covalently binds to BTK and inhibits aberrant B cell receptor signaling. Tirabrutinib can be used in studies of autoimmune diseases and hematological malignancies .

HY-113134S

25-Hydroxycholesterol-d6 25-OHC-d₆	Isotope-Labeled Compounds Endogenous Metabolite	Inflammation/Immunology
25-Hydroxycholesterol-d₆ (25-OHC-d₆) is the deuterium labeled 25-Hydroxycholesterol. 25-Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells[1][2].

HY-143423A

(S)-MALT1-IN-5	MALT1	Inflammation/Immunology Cancer
(S)-MALT1-IN-5 is a potent inhibitor of MALT1 protease. (S)-MALT1-IN-5 inhibits the activity of MALT1 is expected to be able to correct the enhancement of MALT1 activity due to abnormality of T cell receptor signal or B cell receptor signal, and cancer or inflammatory disease caused by MALT1 activity is expected. (S)-MALT1-IN-5 has the potential for the research of MALT1-related diseases (extracted from patent WO2020111087A1, compound 1) .

HY-113962

7α,25-Dihydroxycholesterol 1 Publications Verification 7α,25-OHC	EBI2/GPR183 Endogenous Metabolite	Inflammation/Immunology
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC₅₀=140 pM; K_d=450 pM). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells .

HY-150217

CpG ODN 10101 ODN 10101	Toll-like Receptor (TLR) HCV	Infection Inflammation/Immunology
CpG ODN 10101, a synthetic oligodeoxynucleotide (ODN), is a *toll-like receptor* 9 (TLR9)** agonist. CpG ODN 10101 is a potent inducer of cytokine/chemokine expression ex vivo when used in combination with HH2(VQLRIRVAVIRA-NH2). CpG ODN 10101 induces IFN- secretion from dendritic cells (DCs) and stimulates B-cells.CpG ODN 10101 has antiviral and immunomodulatory properties that can influence chronic infection with HCV .

HY-150593

IRAK4-IN-16	IRAK	Cancer
IRAK4-IN-16 (compound 4) is a potent IRAK4 (interleukin-1 receptor associated kinase 4) inhibitor, with an IC₅₀ of 2.5 nM. IRAK4-IN-16 shows cytotoxicity activity against OCI-LY10, TMD8, Ramos and HT cells, with IC₅₀ values of 0.2, 0.2, 0.6, and 2.7 μM, respectively .

Autoimmune Disease Compound Library	457 compounds
Autoimmune disease is a pathological disease characterized by inflammatory disorders targeting autoantigens. The routine treatment of autoimmune diseases suppresses general immune function to regulate uncontrolled inflammation. The current targeted immunotherapy suppresses the main pro-inflammatory signaling pathways by blocking inflammatory cytokines, cell surface molecules, and intracellular kinases. As key participants in innate immunity, macrophages and dendritic cells (DCs) are crucial for Ag presentation and pro-inflammatory cytokine production, such as TNF and IL-1 β、 IL-6, IL-23, B cell activating factor (BAFF), and the proliferation-inducing ligand (APRIL, also known as TNFSF13A). MCE designs a unique collection of 457 autoimmune disease-related compounds, covering multiple targets and subtypes, such as TNF Receptor, IFNAR, JAK, Btk, TLR, IL-6, IL-17, IL-23, etc. It is a useful tool for screening autoimmune disease drugs.

Protein A SPA	Native Proteins
Protein A (SPA) is an immunoglobulin (Ig) binding protein that exists on the surface of bacteria and can be freely secreted into the extracellular environment. Protein A blocks opsonization and phagocytosis and induces B-cell death in vitro by binding to the Fc region of antibodies and the Fab region of B-cell receptors. Protein A has the ability to inhibit opsonization and phagocytosis in vitro .

CD19 car circRNA-LNP	Drug Delivery
CD19 car circRNA-LNP is a lipid nanoparticle (LNP) containing CD19 car circRNA, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. CD19 car circRNA can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction .

CD19 car mRNA-LNP	Drug Delivery
CD19 car mRNA-LNP is a lipid nanoparticle (LNP) containing CD19 car mRNA, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. CD19 car mRNA can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction .

Cat. No.	Product Name	Target	Research Area

HY-P99446

Atacicept TACI-Ig; TACI-Fc 5	Inhibitory Antibodies	Inflammation/Immunology
Atacicept (TACI-Ig) is a is a recombinant fusion protein containing the extracellular, ligand-binding portion of the TACI receptor and the Fc portion of human IgG. Atacicept inhibits B cell stimulation by binding to B lymphocyte stimulator and a proliferation-inducing ligand. Atacicept can be used in research of B-cell autoimmune disease .

HY-P99400

Samalizumab ALXN 6000	Inhibitory Antibodies	Cancer
Samalizumab (ALXN 6000) is a humanized monoclonal antibody that specifically binds to CD200 and blocks its ligation to the CD200 receptor (CD200R). Samalizumab can be used for multiple myeloma and B-cell chronic lymphocytic leukemia research .

HY-P99338

Tisagenlecleucel CTL019	CD19	Inflammation/Immunology Cancer
Tisagenlecleucel (CTL019) is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. Tisagenlecleucel targets and eliminates CD19-expressing B cells. Tisagenlecleucel can be used for the research of refractory aggressive diffuse large B-cell lymphoma .

HY-P99255

Moxetumomab pasudotox CAT 8015; HA 22	Antibody-Drug Conjugates (ADCs) CD22	Cancer
Moxetumomab pasudotox (CAT 8015) is anti-CD22 immunotoxin containing an anti-CD22 F_v and Pseudomonas exotoxin. CD22 is a cell surface receptor expressed on a variety of malignant B-cells. Moxetumomab pasudotox can be used in the research of hairy cell leukemia (HCL) .

HY-P990046

Tuparstobart Incagn-02385	LAG-3	Inflammation/Immunology
Tuparstobart (Incagn-02385) is an IgG1κ antibody targeting LAG-3. LAG-3 is an immune checkpoint receptor protein mainly expressed on activated T cells, NK cells, B cells and plasmacytoid dendritic cells .

HY-P99487

Briobacept BR 3FC	ADC Antibody	Inflammation/Immunology
Briobacept (BR 3FC) is a selective human monoclonal antibody targeting to BLyS (BAFF), induces B cells apoptosis. Briobacept is a recombinant glucoprotein, consists of 2 molecules from the BLyS receptor (BR3)and a Fc domain of human IgG1. Briobacept can be used in studies of rheumatoid arthritis (RA) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113134

25-Hydroxycholesterol 10+ Cited Publications 25-OHC	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Endogenous Metabolite
25-Hydroxycholesterol (25-OHC) is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC₅₀≈65 nM) and selective suppressor of IgA production by B cells.

HY-113962

7α,25-Dihydroxycholesterol 1 Publications Verification 7α,25-OHC	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	EBI2/GPR183 Endogenous Metabolite
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC₅₀=140 pM; K_d=450 pM). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells .

Species:	Human (18) Virus (1) Rhesus Macaque (4) Mouse (6) Rat (4) Cynomolgus (3)
Tag:	His (22) Avi (4) GST (1) Fc (13) Flag (1)
Source:	HEK293 (34) E. coli Cell-free (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P72019

	Siglec-2/CD22 Protein, Human (HEK293, His) B-cell receptor CD22; BL-CAM; Siglec-2; CD22; SIGLEC2	Human	HEK293
	The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Human (HEK293, His) is the recombinant human-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Siglec-2/CD22 Protein, Human (HEK293, His) is 668 a.a., with molecular weight of 77-110 kDa.

HY-P72474A

	Siglec-2/CD22 Protein, Mouse (HEK293, His) B-cell receptor CD22; BL-CAM; Siglec-2; CD22; Lyb-8	Mouse	HEK293
	Siglec-2/CD22 is a B cell surface receptor that mediates B cell interactions and is involved in B cell localization within lymphoid tissues. It selectively binds α-2,6-linked sialic acids, including CD45, and its sialic acid recognition site may be regulated by cis interactions. Siglec-2/CD22 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Siglec-2/CD22 Protein, Mouse (HEK293, His) is 681 a.a., with molecular weight of 95-130 kDa.

HY-P70560

	Siglec-2/CD22 Protein, Human (668a.a, HEK293, Fc) Siglec-2; CD22; B-cell receptor CD22	Human	HEK293
	The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Human (668a.a, HEK293, Fc) is the recombinant human-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Siglec-2/CD22 Protein, Human (668a.a, HEK293, Fc) is 668 a.a., with molecular weight of 120-150 kDa.

HY-P75626

	CD22 Protein, Rhesus Macaque (HEK293, Fc) B-cell receptor CD22; BL-CAM; CD22; T-cell surface antigen Leu-14	Rhesus Macaque	HEK293
	The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. CD22 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived CD22 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD22 Protein, Rhesus Macaque (HEK293, Fc) is 686 a.a., with molecular weight of ~102.1 kDa.

HY-P75627

	CD22 Protein, Rhesus Macaque (HEK293, His) B-cell receptor CD22; BL-CAM; CD22; T-cell surface antigen Leu-14	Rhesus Macaque	HEK293
	The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. CD22 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived CD22 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD22 Protein, Rhesus Macaque (HEK293, His) is 686 a.a., with molecular weight of ~76.5 kDa.

HY-P77537

	Siglec-2/CD22 Protein, Human (Biotinylated, HEK293, His) B-cell receptor CD22; BL-CAM; Siglec-2; CD22; SIGLEC2	Human	HEK293
	The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-2/CD22 Protein, Human (Biotinylated, HEK293, His) is 687 a.a., with molecular weight of ~76.6 KDa.

HY-P72474

	Siglec-2/CD22 Protein, Mouse (AAA02562.1, HEK293, His) B-cell receptor CD22; BL-CAM; Siglec-2; CD22; Lyb-8	Mouse	HEK293
	Siglec-2/CD22 Protein mediates B-cell B-cell interaction and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2/CD22 Protein, Mouse (AAA02562.1, HEK293, His) is the recombinant mouse-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Siglec-2/CD22 Protein, Mouse (AAA02562.1, HEK293, His) is 681 a.a., with molecular weight of 100-120 kDa.

HY-P73646

	Siglec-2/CD22 Protein, Mouse (690a.a, HEK293, Fc) B-cell receptor CD22; BL-CAM; Siglec-2; CD22; SIGLEC2	Mouse	HEK293
	Siglec-2/CD22 Protein, Mouse (690a.a, HEK293, Fc) is a Siglec of ~140 kDa with seven Ig-like domains and is expressed in a B-cell lineage-specific fashion, starting at the pre-B cell stage. CD22 is associated with membrane-bound IgM on the surface of B cells. Siglec-2 (CD22) specifically recognizes 伪2.6 sialic acid-containing glycans. Siglec-2 negatively regulates B cell antigen receptor (BCR) signaling by recruitment and activation of SH2-containing phosphatase 1 (SHP-1), which counteracts the phospharylation-mediated activation of signaling molecules by dephosphorylation, and reduces Ca²⁺ signaling by regulating the activity of the Ca²⁺ pump PMCA. Siglec-2/CD22 Protein, Mouse (690a.a, HEK293, Fc) is the recombinant mouse-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Siglec-2/CD22 Protein, Mouse (690a.a, HEK293, Fc) is 690 a.a., with molecular weight of ~125 kDa.

HY-P73648

	Siglec-2/CD22 Protein, Human (512a.a, HEK293, His) B-cell receptor CD22; BL-CAM; Siglec-2; CD22; SIGLEC2	Human	HEK293
	The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Human (512a.a, HEK293, His) is the recombinant human-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-2/CD22 Protein, Human (512a.a, HEK293, His) is 512 a.a., with molecular weight of 90-100 kDa.

HY-P77539

	Siglec-2/CD22 Protein, Human (Biotinylated, 512a.a, HEK293, His) B-cell receptor CD22; BL-CAM; Siglec-2; CD22; SIGLEC2	Human	HEK293
	The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Human (Biotinylated, 512a.a, HEK293, His) is the recombinant human-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-2/CD22 Protein, Human (Biotinylated, 512a.a, HEK293, His) is 512 a.a., with molecular weight of ~58.5 KDa.

HY-P75430

	Siglec-2/CD22 Protein, Rat (692a.a, HEK293, His) B-cell receptor CD22; BL-CAM; CD22; T-cell surface antigen Leu-14	Rat	HEK293
	The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Rat (692a.a, HEK293, His) is the recombinant rat-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-2/CD22 Protein, Rat (692a.a, HEK293, His) is 692 a.a., with molecular weight of ~76.7 kDa.

HY-P75431

	Siglec-2/CD22 Protein, Rat (692a.a, HEK293, Fc) B-cell receptor CD22; BL-CAM; CD22; T-cell surface antigen Leu-14	Rat	HEK293
	The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Rat (692a.a, HEK293, Fc) is the recombinant rat-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Siglec-2/CD22 Protein, Rat (692a.a, HEK293, Fc) is 692 a.a., with molecular weight of ~102 kDa.

HY-P78541

	Siglec-2/CD22 Protein, Human (FITC, HEK293, Fc) CD22 molecule; CD22; Siglec-2; B-cell receptor CD22; BL-CAM; SIGLEC2; SIGLEC2FLJ22814	Human	HEK293
	Siglec-2/CD22 Protein mediates B-cell interactions, potentially guiding B-cell localization within lymphoid tissues. Recognizing sialylated glycoproteins, especially alpha-2,6-linked sialic acid, it engages in cis interactions on the cell surface. During the immune response, ligand-induced tyrosine phosphorylation suggests its role in B-cell antigen receptor signaling. Siglec-2/CD22 acts positively through Src kinases and inhibits by recruiting phosphatases. Existing as a monomer or heterodimer, its interactions with key molecules highlight a pivotal role in complex B-cell signaling. Further research is essential for precise molecular pathways and functional consequences. Siglec-2/CD22 Protein, Human (FITC, HEK293, Fc) is the recombinant human-derived Siglec-2/CD22 protein, expressed by HEK293, with C-hFc labeled tag. The total length of Siglec-2/CD22 Protein, Human (FITC, HEK293, Fc) is 668 a.a., with molecular weight of 130-140 kDa.

HY-P700895

	Siglec-2/CD22 Protein, Rhesus macaque (HEK293, His) CD22 molecule; CD22; Siglec-2; B-cell receptor CD22; BL-CAM; SIGLEC2; SIGLEC2FLJ22814	Rhesus Macaque	HEK293
	The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Rhesus macaque (HEK293, His) is the recombinant Rhesus Macaque-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-2/CD22 Protein, Rhesus macaque (HEK293, His) is 667 a.a., with molecular weight of 100-120 kDa.

HY-P72351

	Siglec-2/CD22 Protein, Human (Biotinylated, HEK293, His-Avi) B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigenMGC130020; CD22; T-cell surface antigen Leu-14	Human	HEK293
	The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of Siglec-2/CD22 Protein, Human (Biotinylated, HEK293, His-Avi) is 668 a.a., with molecular weight of 110-130 kDa.

HY-P71684

	BCAP31 Protein, Human (GST) 6C6 AG; 6C6 AG tumor associated antigen; B-cell receptor-associated protein 31; BA31; CDM; CDM protein; DXS1357E; MS950; p28; p28 Bap31; Protein CDM; RP23-329M9.5	Human	E. coli
	The BCAP31 protein acts as a chaperone and is one of the most abundant endoplasmic reticulum (ER) proteins. The BCAP31 protein also serves as a cargo receptor for transmembrane protein export. BCAP31 stimulates the translocation of NDUFS4 and NDUFB11 to mitochondria, interacts with BCL2, and may be involved in caspase-8-mediated apoptosis. BCAP31 Protein, Human (GST) is the recombinant human-derived BCAP31 protein, expressed by E. coli , with N-GST labeled tag. The total length of BCAP31 Protein, Human (GST) is 242 a.a., with molecular weight of ~54.5 kDa.

HY-P70559

	Siglec-2/CD22 Protein, Human (668a.a, HEK293, His) B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigenMGC130020; CD22 molecule; CD22; sialic acid binding Ig-like lectin 2; Siglec-2; SIGLEC2FLJ22814; T-cell surface antigen Leu-14	Human	HEK293
	The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Human (668a.a, HEK293, His) is the recombinant human-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Siglec-2/CD22 Protein, Human (668a.a, HEK293, His) is 668 a.a., with molecular weight of 100-140 kDa.

HY-P72707

	CD79B Protein, Mouse (HEK293, Fc) B-cell antigen receptor complex-associated protein beta chain; CD79b; B29; IGB	Mouse	HEK293
	CD79B protein, together with CD79A, initiates the B-cell antigen receptor complex (BCR) signaling cascade, which is critical for complex internalization and transport to late endosomes, promoting antigen presentation. CD79B enhances CD79A phosphorylation, possibly recruiting kinases or protective proteins. CD79B Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CD79B protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD79B Protein, Mouse (HEK293, Fc) is 133 a.a., with molecular weight of 50-65 kDa.

HY-P72709

	CD79A Protein, Human (HEK293, His) B-cell antigen receptor complex-associated protein alpha chain; CD79a; IGA; MB1	Human	HEK293
	The CD79A protein is critical for initiating the B cell antigen receptor complex (BCR) signaling cascade upon antigen binding. It promotes internalization, transport to late endosomes, and antigen presentation of BCR complexes. CD79A Protein, Human (HEK293, His) is the recombinant human-derived CD79A protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD79A Protein, Human (HEK293, His) is 111 a.a., with molecular weight of 25-40 kDa.

HY-P75383

	CD79A Protein, Mouse (HEK293, Fc) B-cell antigen receptor complex-associated protein alpha chain; CD79a; IGA; MB1	Mouse	HEK293
	CD79A cooperates with CD79B to initiate the B cell antigen receptor complex (BCR) signaling cascade upon antigen binding. This results in complex internalization, transport and antigen presentation. CD79A Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CD79A protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD79A Protein, Mouse (HEK293, Fc) is 109 a.a., with molecular weight of ~39 kDa.

HY-P75658

	CD79B Protein, Rat (HEK293, Fc) B-cell antigen receptor complex-associated protein beta chain; CD79b; B29; IGB	Rat	HEK293
	CD79B Protein, also known as B29 or Igβ, is an essential component of the B cell receptor along with immunoglobulin and mb1 (Igα, CD79a) and is absolutely required for B cell development. Rat CD79B protein comprises 228 amino acids, and its amino acid sequence is 85 and 69% identical with the mouse and human counterparts, respectively. The B-cell antigen receptor (BCR) signaling component Igβ (CD79B) and the co-receptor CD19 act as an alternative B-cell signaling module that promotes the survival of B lymphoma and normal B cells via integrated ITAM/PI3K signaling. The loss of CD79B causes a block in N-glycan maturation and accumulation of immature proteins. CD79B Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD79B protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD79B Protein, Rat (HEK293, Fc) is 133 a.a., with molecular weight of ~50 kDa.

HY-P75659

	CD79B Protein, Rat (HEK293, His) B-cell antigen receptor complex-associated protein beta chain; CD79b; B30; IGB	Rat	HEK293
	CD79B Protein, also known as B29 or Igβ, is an essential component of the B cell receptor along with immunoglobulin and mb1 (Igα, CD79a) and is absolutely required for B cell development. Rat CD79B protein comprises 228 amino acids, and its amino acid sequence is 85 and 69% identical with the mouse and human counterparts, respectively. The B-cell antigen receptor (BCR) signaling component Igβ (CD79B) and the co-receptor CD19 act as an alternative B-cell signaling module that promotes the survival of B lymphoma and normal B cells via integrated ITAM/PI3K signaling. The loss of CD79B causes a block in N-glycan maturation and accumulation of immature proteins. CD79B Protein, Rat (HEK293, His) is the recombinant rat-derived CD79B protein, expressed by HEK293 , with C-His labeled tag. The total length of CD79B Protein, Rat (HEK293, His) is 133 a.a., with molecular weight of 25-30 kDa.

HY-P72708

	CD79B Protein, Rhesus Macaque (HEK293, His) B-cell antigen receptor complex-associated protein beta chain; CD79b; B29; IGB	Rhesus Macaque	HEK293
	CD79B protein binds to CD79A and initiates the B cell antigen receptor complex (BCR) signaling cascade. This results in complex internalization, transport to late endosomes and antigen presentation. CD79B Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived CD79B protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD79B Protein, Rhesus Macaque (HEK293, His) is 132 a.a., with molecular weight of 20-30 kDa.

HY-P75385

	CD79 Protein, Mouse (HEK293, His) B-cell antigen receptor complex-associated protein; CD79a; IGA; MB1; CD79b; IGB	Mouse	HEK293
	CD79A, collaborating with CD79B, initiates the B-cell antigen receptor complex (BCR) signal cascade upon antigen binding. This leads to complex internalization, trafficking, and antigen presentation. Essential for BCR surface expression and B-cell differentiation, CD79A stimulates SYK activation, binds BLNK, and enhances Src-family kinase activity. It represses BCR signaling during immature B-cell development. As a disulfide-linked complex, CD79A forms the BCR with alpha/beta chain heterodimer and membrane-bound immunoglobulin. CD79 Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived CD79 protein, expressed by HEK293, with C-His labeled tag. CD79 Protein, Mouse (HEK293, His), has molecular weight of ~34.6 & 28.3 & 24.1 kDa, respectively.

HY-P75386A

CD79 Protein, Human (HEK293, His)

B-cell antigen receptor complex-associated protein; CD79a; IGA; MB1; CD79b; IGB
Human HEK293

HY-P75386

	CD79 Protein, Human (HEK293, Flag-His) B-cell antigen receptor complex-associated protein; CD79a; IGA; MB1; CD79b; IGB	Human	HEK293
	CD79A Protein is crucial for initiating the B-cell antigen receptor complex (BCR) signal transduction cascade upon antigen binding. It facilitates BCR complex internalization, trafficking to late endosomes, and antigen presentation. CD79A ensures BCR surface expression, pro- and pre-B-cell differentiation, and autophosphorylation of SYK by binding to BLNK. It interacts with FYN and LYN kinases, enhancing their activity. CD79A, forming a disulfide-linked heterodimer with CD79B, constitutes the BCR complex. It interacts with SYK and BLNK, orchestrating essential signaling events in B-cell development. CD79 Protein, Human (HEK293, Flag-His) is a recombinant protein dimer complex containing human-derived CD79 protein, expressed by HEK293, with C-His, C-Flag labeled tag. CD79 Protein, Human (HEK293, Flag-His), has molecular weight of ~37.5 kDa.

HY-P70778

	BCMA/TNFRSF17 Protein, Cynomolgus (HEK293, His) Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; Tnfrsf17; Bcm; Bcma	Cynomolgus	HEK293
	B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is used as a biomarker for Multiple myeloma (MM). BCMA mainly plays an important role in B cells for their proliferation, survival and also differentiates them into plasma cells. BCMA/TNFRSF17 Protein, Cynomolgus (HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 53 amino acids (M1-A53) and is produced in HEK293 cells.

HY-P70827

	BCMA/TNFRSF17 Protein, Human (HEK293, mFc) Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; Tnfrsf17; Bcm; Bcma	Human	HEK293
	B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is used as a biomarker for Multiple myeloma (MM). BCMA mainly plays an important role in B cells for their proliferation, survival and also differentiates them into plasma cells. BCMA/TNFRSF17 Protein, Human (HEK293, mFc) is a recombinant protein with a C-Terminal Fc label, It consists of 54 amino acids (M1-A54) and is produced in HEK293 cells.

HY-P72342

	BCMA/TNFRSF17 Protein, Human (Biotinylated, HEK293, Fc-Avi) Tumor necrosis factor receptor superfamily member 17; TNFRSF17; B-cell maturation protein; CD269	Human	HEK293
	B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is used as a biomarker for Multiple myeloma (MM). BCMA mainly plays an important role in B cells for their proliferation, survival and also differentiates them into plasma cells. BCMA/TNFRSF17 Protein, Human (Biotinylated, HEK293, Fc-Avi) is a biotinylated recombinant protein with a C-Terminal Avi label and a C-Terminal Fc label, It consists of 54 amino acids (M1-A54) and is produced in HEK293 cells.

HY-P7654

	BCMA/TNFRSF17 Protein, Human (HEK293, Fc) rHuCMA/TNFRSF17, C-Fc; Tumor necrosis factor receptor superfamily member 17; TNFRSF17; B-cell maturation protein	Human	HEK293
	B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is used as a biomarker for Multiple myeloma (MM). BCMA mainly plays an important role in B cells for their proliferation, survival and also differentiates them into plasma cells. BCMA/TNFRSF17 Protein, Human (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 54 amino acids (M1-A54) and is produced in HEK293 cells.

HY-P70541

	CD79B Protein, Human (HEK293, His) B-cell Antigen receptor Complex-Associated Protein Beta Chain; B-cell-Specific Glycoprotein B29; Ig-Beta; Immunoglobulin-Associated B29 Protein; CD79b; CD79B; B29; IGB	Human	HEK293
	CD79B protein binds to CD79A and initiates the B cell antigen receptor complex (BCR) signaling cascade. This results in complex internalization, transport to late endosomes and antigen presentation. CD79B Protein, Human (HEK293, His) is the recombinant human-derived CD79B protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD79B Protein, Human (HEK293, His) is 131 a.a., with molecular weight of 25-36 kDa.

HY-P70768

	CD79B Protein, Human (Biotinylated, HEK293, His-Avi) B-cell Antigen receptor Complex-Associated Protein Beta Chain; B-cell-Specific Glycoprotein B29; Ig-Beta; Immunoglobulin-Associated B29 Protein; CD79b; CD79B; B29; IGB	Human	HEK293
	CD79B protein binds to CD79A and initiates the B cell antigen receptor complex (BCR) signaling cascade. This results in complex internalization, transport to late endosomes and antigen presentation. CD79B Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD79B protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of CD79B Protein, Human (Biotinylated, HEK293, His-Avi) is 131 a.a., with molecular weight of 30-40 kDa.

HY-P78091

	CD40 Protein, Human (Biotinylated, HEK293, His-Avi) CD40; CD40L receptor; TNFRSF5; B cell surface antigen CD40; B-cell surface antigen CD40; Bp50B cell-associated molecule; CD40 antigen; CD40 molecule, TNF receptor superfamily member 5; CD40 type II isoform; CDw40; MGC9013; nerve growth factor receptor-relat	Human	HEK293
	CD40 protein is a TNFSF5/CD40LG receptor that transduces signals through TRAF6 and MAP3K8-mediated pathways, activates ERK in macrophages and B cells, and induces immunoglobulin secretion. CD40 exists as monomers and homodimers and interacts with TRAF proteins (TRAF1, TRAF2, TRAF3, TRAF5, and TRAF6). CD40 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD40 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of CD40 Protein, Human (Biotinylated, HEK293, His-Avi) is 173 a.a., with molecular weight of 35-40 kDa.

HY-P7839

	BCMA/TNFRSF17 Protein, Cynomolgus (HEK293, Fc) rCynBCMA-Tall_bind domain-containing protein/BCMA, Fc; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; Tnfrsf17; Bcm; Bcma	Cynomolgus	HEK293
	B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is used as a biomarker for Multiple myeloma (MM). BCMA mainly plays an important role in B cells for their proliferation, survival and also differentiates them into plasma cells. BCMA/TNFRSF17 Protein, Cynomolgus (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 53 amino acids (M1-A53) and is produced in HEK293 cells.

HY-P7837

	CD40 Protein, Cynomolgus (HEK293, Fc) rCynB-cell surface antigen CD40, Fc; Tumor Necrosis Factor receptor Superfamily member 5; B-cell Surface Antigen CD40; Bp50; CD40L receptor; CDw40; CD40; TNFRSF5	Cynomolgus	HEK293
	CD40 Protein, a vital TNFR superfamily member, lacks conserved residue(s) crucial for feature annotation propagation, indicating unique structural attributes. This distinctiveness may influence CD40's functional interactions within the TNFR superfamily, underscoring the need for further exploration to unravel its specific roles and regulatory mechanisms in cellular signaling pathways. CD40 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived CD40 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD40 Protein, Cynomolgus (HEK293, Fc) is 173 a.a., with molecular weight of 48-60 kDa.

HY-P702484

	U51 Protein, HHV-6 variant B (Cell-Free, His) G-protein coupled receptor homolog U51	Virus	E. coli Cell-free
	U51 is a member of the G-protein coupled receptor 1 family. U51 Protein, HHV-6 variant B (Cell-Free, His) is the recombinant Virus-derived U51 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of U51 Protein, HHV-6 variant B (Cell-Free, His) is 301 a.a., with molecular weight of 37.3 kDa.

Cat. No.	Product Name	Chemical Structure

HY-113134S

25-Hydroxycholesterol-d6
25-Hydroxycholesterol-d₆ (25-OHC-d₆) is the deuterium labeled 25-Hydroxycholesterol. 25-Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells[1][2].

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